Scientific and Clinical Advisory Board

Taylor Schreiber, M.D., Ph.D.

Chairman

As Heat Biologics’ former Chief Scientific Officer, Dr. Schreiber is co-inventor of significant elements of the company’s ImPACT and ComPACT immunotherapy platforms.  He most recently joined Shattuck Labs, Inc., a biotechnology company focused on developing technology exclusively licensed from Heat, as their Chief Scientific Officer.  Taylor was also a scientific founder of Pelican Therapeutics, which developed a first-in-class agonist antibody to human TNFRSF25.  As a cancer biologist and drug development scientist, Dr. Schreiber possesses over 15 years of laboratory experience in the discovery of novel therapeutic immuno-oncology compounds.  Dr. Schreiber received his Ph.D. from the Sheila and David Fuente Program in cancer biology as well as his M.D. at the University of Miami Miller School of Medicine.  In addition, he completed his post-doctoral fellowship with the original inventor of Heat’s ImPACT technology platform, Eckhard R. Podack, M.D., Ph.D., studying the immunobiology of TNFRSF25.  Dr. Schreiber has authored over 30 peer-reviewed tumor immunology and heat shock protein-based cancer immunotherapy publications. 

Gary Acton, M.D.

Member

Dr. Acton is a London based clinician providing oncology drug development advice, predominantly to US and European biotechnology companies. Twenty years of pharmaceutical experience have left him with wide ranging clinical, commercial and corporate capabilities. He has expertise in all stages of drug development and through into the marketplace. This includes successful US NDA and European MAA approvals. Dr. Acton has been involved in drug development programs for most solid and hematological malignant indications. He has worked in North American, European, and Japanese pharmaceutical companies. Dr. Acton has served at Board level in both private and publicly traded entities. He originally studied medicine at Oxford and London Universities. Prior to moving into the pharmaceutical industry, Dr. Acton obtained a number of post-graduate qualifications while undergoing general medical and oncology training at a variety of London teaching hospitals.

Roger Cohen, M.D.

Member

Dr. Cohen is Professor of Medicine at the University of Pennsylvania and Associate Director for Clinical Research for the Abramson Cancer Center. He is a graduate of Harvard Medical School and completed internal medicine and hematology training at Mount Sinai Hospital (NY) followed by research fellowships at the Memorial Sloan-Kettering Cancer Center and National Institutes of Health and a medical oncology fellowship at the National Cancer Institute. He was a medical officer at the FDA Center for Biologics from 1989-1994 where he was Deputy Director, Division of Monoclonal Antibodies. Prior to his arrival at Penn, Dr. Cohen was Director of the Clinical Trials Office at the University of Virginia Cancer Center in Charlottesville and then Director of the Phase 1 Program at the Fox Chase Cancer Center where he also served as interim Medical Oncology Department Chair for more than 2 years. He is an active investigator on a number of first-in-humans clinical trials with research interests that focus on evaluation of novel therapies, including monoclonal antibodies, immune therapies, and small molecule cell-signaling pathway inhibitors. He primarily sees patients with lung and head and neck cancer.

Kapil Dhingra, M.D.

Member

Dr. Dhingra has over 25 years of experience in oncology clinical research and drug development, including nine years at Roche Pharmaceuticals, where he played a key role in the expansion of Roche Oncology.  He served in several management positions at Roche, including Vice President, Head, Oncology Disease Biology Leadership Team, and Head, Oncology Clinical Development.  Prior to his time at Roche, Dr. Dhingra worked as a senior clinical research physician at Eli Lilly and Company, as well as served as Assistant Professor at MD Anderson Cancer Center and Clinical Associate Professor at Indiana University School of Medicine.  Dr. Dhingra is currently managing member and founder of KAPital Consulting, a healthcare consulting firm, as well as serves as an advisor to and/or member of the board of the directors for several emerging life science companies.  He holds an M.B.B.S. (equivalent to an M.D. in the U.S.) from the All India Institute of Medical Sciences.

Llew Keltner, M.D., Ph.D.

Member

Dr. Keltner has been the Chief Executive Officer of AgonOx, a biotech company developing OX40 agonists for use in cancer therapy. Dr. Keltner was the President of Novici Biotech, a privately-held gene and protein optimization firm. He is also Chief Executive Officer of EPISTAT, an international healthcare technology transfer, corporate risk management, and healthcare strategy company that he founded in 1972. Dr. Keltner was Chief Executive Officer and President of Light Sciences Oncology, a privately-held biotechnology company developing a late stage, light-activated therapy for hepatocellular cancer and other solid tumors from 2001 to 2010. From 1997 to 2004, Dr. Keltner was Chief Executive Officer of Metastat, a development-stage biotech company focused on cancer metastasis. He is currently a member of the American Society of Clinical Oncology, American Medical Association, International Association of Tumor Marker Oncology, American Association of Clinical Chemistry, and Drug Information Association. Dr. Keltner received an M.S. in Epidemiology and Biostatistics, a Ph.D. in Biomedical Informatics, and an M.D. from Case Western Reserve University in Cleveland, Ohio. Dr. Keltner has also authored several research publications.

Mark Schoenberg, M.D.

Member

Dr. Schoenberg is Chairman of the Department of Urology at Montefiore Medical Center and Albert Einstein College of Medicine of Yeshiva University, Bronx, New York.  His clinical practice is centered on the care of patients with invasive bladder cancer. Formerly he was the Bernard L. Schwartz Distinguished Professor of Urologic Oncology at The Johns Hopkins University.  Dr. Schoenberg’s research program has focused on the translational validation of urinary markers for the early detection of cancer, the development of regenerative medicine solutions to the challenges of lower urinary tract reconstruction, and minimally invasive therapies for urologic malignancies. He is the past chair of the Medical Advisory Board of the Bladder Cancer Advocacy Network, author of The Guide to Living with Bladder Cancer, co-editor of The Textbook of Bladder Cancer, a contributor to Campbell’s Urology , and former seminars editor of the journal Urologic Oncology. Dr. Schoenberg has served as principal investigator and co-investigator on numerous clinical trials and from 2005-2009 served as the national principal investigator for the Early Detection Research Network (EDRN/NCI) validation trial of microsatellite analysis for bladder cancer detection. He received his M.D. from the University of Texas Health Science Center and completed residency at the Hospital of the University of Pennsylvania and a basic research and clinical urologic oncology fellowship at Johns Hopkins. 

Justin Stebbing, M.D., M.A., FRCP, FRC Path, Ph.D.

Member

Dr. Stebbing is a Professor of Cancer Medicine and Oncology, and a Consultant Oncologist at Imperial College and Imperial College Healthcare NHS Trust. He is a Fellow of the Royal College of Pathologists, the Royal College of Physicians and the American Board of Internal Medicine. Dr. Stebbing sits on advisory boards of several international cancer committees and chairs the World Vaccine Congress. He trained in medicine at Trinity College Oxford, obtaining a triple first class degree. After completing his residency at The Johns Hopkins Hospital in the United States, Dr. Stebbing returned to London to continue his training in oncology at The Royal Marsden and St. Bartholomew's Hospitals. Funded by the Medical Research Council, he undertook a Ph.D. investigating the interplay between cancer and the immune system. Specifically, Dr. Stebbing focused on heat shock proteins in viral infections and tumorigenesis. His research aided in the development of several vaccines currently in clinical trials.

Dr. Stebbing has published over 400 peer-reviewed papers, the majority of which as first or last author, in journals such as  The Lancet, The New England Journal of Medicine, Blood, Journal of Clinical Oncology and Annals of Internal Medicine, and has authored more than 100 book chapters. His work has primarily addressed early and late stage trials of new drugs, mechanisms of disease and prognostic indicators. He is also on the editorial board of several world-class journals, including the Journal of Clinical Oncology.