Pelican’s PTX-35 is a humanized monoclonal antibody that is a functional agonist of human TNFRSF25. This antibody provides highly selective and potent stimulation of ‘memory’ CD8+ cytotoxic T-cells. This is the class of T-cell that is responsible for eliminating tumor cells in patients. Due to the preferential specificity of PTX-35 to CD8+ T-cells, this agent represents a promising candidate as a T-cell co-stimulator in cancer patients.
For more information on Pelican and PTX-35, please visitwww.pelicantherapeutics.com